A couple with normal phenotype has been married for 3 years with three spontaneous abortions but the karyotype analysis showed no obvious abnormality. According to the doctor's recommendation, the couple's 5 embryos were tested by PGT-A after ovarian hyperstimulation by drug stimulation, egg retrieval, insemination, in vitro culture of fertilized eggs, embryo biopsy, embryo freezing. The results indicated that two (No.3 and No.5) were normal and three (No.1, No.2 and No.4) were abnormal in chromosomes. Abnormalities included trisomy, monosomy and large chromosomal deletions. After a comprehensive evaluation of the two normal embryos, the doctor finally selected No.5 for implantation. 14 days after implantation, the test showed that the patient had a successful pregnancy, and the prenatal diagnosis was consistent with the PGT-A results. Finally, the pregnant woman gave birth to a healthy baby after a long gestation. Through PGT-A, the couple avoided the physiological, psychological and economic losses to the whole family brought about by repeated abortions, and also avoided the heavy burden on society caused by the babies with genetic diseases.
How does the basecare PGT-A product works?
Basecare will work closely with your reproductive endocrinologist and IVF laboratory to test each of your embryos for aneuploidy.
Preimplantation genetic testing (PGT) can help identify the embryos that are most suitable for transfer during IVF to give you the best chance of implantation and a successful pregnancy. This test works by identifying embryos with extra or missing chromosomes or pieces of chromosomes.
Who benefits form PGT-A?
Infertile women of advanced maternal age (typically 38 or older)
Women who have had recurrent miscarriages(≥2 times)
People who have experienced previous IVF failure
The first PGT-A kit approved by CFDA (Approval No. 20203400181)
for each client family as high as 400000 yuan of medical insurance, to reassure client for pregnancy
Comprehensive chromosome screening
It is the first detection method based on NGS and fills the clinical gap in CCS.
Advanced EDCBS algorithm
The first EDCBS algorithm to build the data analysis process of embryo chromosomes in IVF, increases the accuracy of chromosome abnormality detection to over 98%.
Innovative SDWGA technology
The SDWGA technology (Strand Displacement Whole Genome Amplification) to realize 98% amplification uniformity at the whole genome level.