A couple, married for three years, had two abortions. Karyotype analysis results showed that the husband is the reciprocal translocation carrier, the karyotypes were 46, XY, t (3; 7) (q21; q22). The male’s translocation was inherited from his father; The female had a normal karyotype. The couple followed the doctor's advice to try PGT-SR detection. Researchers used PGH technology to detect spouses, male’s father and seven embryos at the same time. Through high-throughput whole genome chip technology combined with family haplotype linkage analysis, they finally obtained two normal embryos for implantation.