We are a very happily married couple since three years, unfortunately! I had two abortions spontaneously. The Karyotype analysis results showed that my husband is the reciprocal translocation carrier, the karyotypes were 46, XY, t (3; 7) (q21; q22). My husband’s translocation was inherited from his father. My results were opposite and very normal. So finally we planned to follow the doctor's advice and try PGT-SR detection. I did my research about PGT-SR “People with chromosome rearrangements are at an increased risk of producing embryos with the incorrect amount of genetic material, which typically do not lead to a successful pregnancy.” Researchers used PGH technology to detect my seven embryos. Through high-throughput whole genome chip technology combined with family haplotype linkage analysis, finally they obtained two normal embryos for implantation. Finally, I had a healthy pregnancy and delivered a baby boy.
Preimplantation Genetic Testing For Structural Rearrangement
Basecare geneticists will work closely with your fertility care team to secure sample cells for testing, and provide you with a detailed report and access to a genetic counselor to help you understand the test results. PGT-SR is a genetic test that can determine whether embryos created through IVF with the incorrect chromosome number or structure. PGT-SR allows your fertility experts to confidently transfer only one embryo at a time and can greatly improve the chance of a successful pregnancy.
Who benefits form PGT-SR?
People who had a child or pregnancy with a chromosome rearrangement
People who are carriers of Inversion
People who are carriers of Reciprocal translocation
People who are carriers of Robertsonian translocation
No pre-experiment, one test and analysis are required for testing
No need waste embryos, suitable for most genetic disease carrier families
Applicable to various chromosomes structural variations
Next-generation sequencing technology, increased 50% SNP site
Test report will be issued within 20 working days
Haplotype analysis model won national patent award