A couple had been married for 2 years and still not pregnant. The doctor suggested that a routine examination should be performed first. The results showed that the man had severe oligozoospermia. In order to further clarify the cause, the man undergoes a Y chromosome microdeletion test. After comprehensive consideration, the doctor suggested that the patient obtains sperm by TESE and conceive children through PGS technology. Finally, the couple had successfully given birth to a healthy baby girl.
Y Chromosome Microdeletion Testing
According to WHO, almost 15% of the couples suffers from infertility world widely; amongst male contribute to 50% and 30% of which are hereditary factors. For spermatogenic disorders causing infertility, Y chromosome microdeletion is the main genetic factor, second to Klinefelter's Syndrome. While deletion of AZFa, AZFb, AZFc regions of Y chromosome often result in male infertility.
Infertility males with cryptorchidism
Pre-operation for infertility males (varicocele)
Infertility males before undergoing ICSI or IVF
Preoperative testicular biopsy for azoospermia
The size and location of AZF missing area can be clearly identified
Simultaneously testing dozens of samples, more convenient for clinical application
Covering all regions of the Y chromosome and other 45 chromosomes
Test report will be issued within 20 working days
Supplementary reports suggest other abnormalities
Appropriate diagnosis scheme based on genetic testing results